Breast
Cystic swellings of the breast
Inflammatory
Acute bacterial mastitis
Neoplastic
Benign- phylloides tumor
Malignant- Intracystic carcinoma
Non neoplastic
Fibroadenosis
Simple cyst of breast
Retention cyst of breast- galactocele
Others
Tuberculous mastitis
Lymphatic cyst of breast
Hydratid cyst of breast
Haemotoma of breast.
Fibroadenoma
Benign tumor of the breast.
Epithelium in a fibrous stroma.
It is an aberration in the normal breast.
Types
Intracanalicular (less fibrous, deep)
Pericanalicular (nor fibrous, superficial)
1 cm or smaller -normal
1-3 cm - large
More than 3- giant
Clinical features
- peak age 20 yrs
- Usually a single lobe
- Painless
- well defined, capsule
- freely moves throughout the breast (breast mouse) -not in elderly.
Treatment -
Excision- Pericanalicular is by Peri areolar incision
Intracanalicular is by sub mamillar incision.
Complication - breast ca.
Phylloides tumor
Fibroepithelial tumors
Also called cystosarcoma fibroid
Capable of attaining massive sizes.
Types- benign, borderline, malignant.
Clinical features
30-40 yrs age
Rapid growth
Stretched skin
Engorged veins
Bosselated appearance
Diagnosis
Clinical, ultrasound, trucut biopsy
Treatment
Excision
Malignant- mastectomy may be necessary
Difference from carcinoma-
Is not attached to skin or pectorals
Can cause multiple cysts due to necrosis
No nipple retraction
Histology- blanching pattern (leaf like)
Breast abscess
Acute bacterial mastitis
Antibioma
Retro maxillary abscess
Sub areolar abscess
Tuberculous abscess
Acute bacterial mastitis
Etiology
Lactational mastitis
Cracks or fissures in the nipple
Haematoma-
Bacteria like staphylococci can infect haemotoma, can also proliferate intraductally and clot milk.
Non lactational- anaerobic bacterial causes. Occurs in patients with ductal ectasia and subareolar mastitis.
Other factors- diabetes, HIV.
Clinical features
Stage of cellulitis- Inflamed, tender, tense, warm breast.
Stage of Abscess- fever, chills - cystic swelling develops untreated- rupture- necrosis- ulcer+ discharge.
Signs- fluctuations may be positive.
Treatment-
Stage of cellulitis
Cloxicillin, NSAIDs - ibuprofen
Stage of abscess
Incision and drainage with antibiotic cover, if both breasts are affected- boil the milk and use.
Complication- abscess, necrosis and
Antibioma- when I and C is done without antibiotic cover, it is replaced by fibrous tissue leading to a firm/hard lump, its treated by excision.
Discharge per nipple
Classification
Types of discharge
Serous- fibrocystic disease, duct ectasia.
Milk- lactation, hyper prolactinoma
Blood- duct ectasia, papiloma
Green- duct ectasia
Yellow- abscess
Site
Unilateral- duct ectasia, fibrocystic - bilateral
With mensuration- fibrocystic
With mass- tender- fibrocystic, non tender- carcinoma
Spontaneous discharge- papiloma.
Investigation and management
Ultrasound, mammogram
TSH, prolactin
Examination of discharge.
- rule out carcinoma, antibiotics, core excision.
Galactorrhea
Discharge of milk from nipples other than breast feeding
Physiological Causes- stimulation during sex
Drugs-
Oral contraceptives
Anti hypertensives
Galactocele
-sub areolar retention cyst
- due to accumulation of milk
- blocked lactiniferous ducts by epithelial debris
- rarely undergoes calcification
-treatment -multiple aspirations.
Or lastly excision
gynecomastia
Unphysiological enlargement of male breast
(Physiological- obesity, adolescence)
Causes
M- malignancy
A-anorchism- absence of testis
S-sex chromosomal anomaly klinefelter's
T-tablets- cimentidine, stibesterol
I-idiopathy
A- atrophied testis(polio, liver failure)
Clinical features- enlarged tender breast, unilateral or bilateral
Examination of testis and liver function.
Treatment- lumpectomy or mastectomy with preserved nipples.
Etiology of breast carcinoma
Sex- women (100:1)
Age- above 35
Race- white
Genes- BRCA1, BRCA2
Diet- obesity
Hormones- early puberty late menopause is a risk factors
More the lactational period lesser the risk.
Hormone replacement therapy
Chest wall radiation- multiple cheast wall
Pathogenesis of breast cell ca
Scirrhous carcinoma
60-75 percent.
Fibrous reaction.
Hard lump.
Retraction of nipple.
Fixidity to skin and chest wall.
While necrosis and calcification
Occurs.
Histology- round or polygon cells.
Sometimes causes atrophic infiltrating ca.
Medullary carcinoma breast
15% of the breast ca
Soft to firm, undifferentiated cells, lymphatic infiltration, good prognosis.
Inflammatory ca
Less than 1%,
Lymphatic infiltration is present.
Rapidly growing tumor comes under local advanced breast carcinoma.
During Lactation and pregnancy
Pain, redness and enlargement present,
different from abscess by lack of fever and presence of peau d' orange.
Worst prognosis.
Paget's disease of nipple
Misnomer.
Carcinoma of the ducts
Unilateral, affects elderly women.
Causes fissures, cracks, ulcers in the nipple, sometimes completely destroyed.
Hyperchromatic halo cell (mucopolysacchsrides or Paget's cell is present)
Colloid ca
Production of mucin
Good prognosis.
Clinical classification and grading of breast cell ca.
Clinical features
Investigations
Management
Advanced breast cell carcinoma
Mastectomy.